The P2-0091 program focuses on the development of advanced inorganic materials with novel functional properties for applications in electronics, energy, and medicine. The main research areas include:
(i) functionalization of silicon for electronic applications;
(ii) development of materials for photoelectrochemical water splitting and thermal insulation; and
(iii) novel antimicrobial and biocompatible materials for medical applications.
The program supports the goals of sustainable development, the European Green Deal, and the national Smart Specialization Strategy, with a strong emphasis on industry collaboration, environmental protection, and the improvement of public health.
Within the Regenesis and BoneFiller projects, the research focuses on the design of instructive and functional biomaterials as part of innovative, minimally invasive therapeutic strategies for the repair of small bone defects (BoneFiller) and enhanced osteochondral regeneration (Regenesis). The technology is based on bioactive and mechanotransductive biomaterials capable of actively responding to body motion, releasing bioactive components, and generating stimuli that promote cell interaction. The biomaterials are designed to support cellular growth and to promote critical phases of regeneration, particularly by enhancing mesenchymal stem cell differentiation, regulating the osteoblast–osteoclast balance, and stimulating osteogenic differentiation. Furthermore, their properties are tailored to support an antiresorptive role during mineralization, maintain bone density and matrix quality, and preserve the mechanical integrity of bone tissue, thereby optimizing the regeneration process. The fundamental concept of biomaterial design is based on exploring and mimicking the chemistry of natural bone tissue. The materials are therefore developed as bone-like calcium phosphates integrated within a polymeric matrix. Special attention is given to architectural design, structural characteristics, and mechanical properties, which are carefully adjusted to meet the requirements of the targeted application. The research involves close collaboration with highly skilled experts, active participation in international consortia, and consultative cooperation with leading scientists in the field who serve as members of the advisory board.